张恒木 研究员、博士，病毒生物学研究室主任。1995-1998年在华东师范大学化学与生命科学院获得硕士学位，1998年-2001年在浙江大学农业与生物技术学院获得博士学位，2001年-2003年期间在清华大学理学院生物科学与技术系从事博士后研究工作，2003年底作为学科带头人引进到浙江省农业科学院工作，2008年10月-2014年10月间先后三次作为高级访问学者在英国剑桥大学进修并开展合作研究。主要研究方向为病毒病原鉴定、病毒致病分子机制、寄主抗病毒机制与抗病毒新种质创制、病毒技术与病毒病绿色防控技术研发与推广。先后主持了浙江省重点自然科学基金、863、国家科技支撑计划、国际合作项目、国家自然科学基金、国家区域创新联合基金等十多个科研项目。从分子水平上探明我国发生的水稻黑条矮缩病和玉米粗缩病病原同为水稻黑条矮缩病毒（RBSDV），澄清了我国对两病病原的长期混淆, 并深入揭示了RBSDV侵染寄主水稻的机制；率先测定了RBSDV、RGDV、SRBSDV等重要水稻病毒的全基因组序列，为同类病害的检测与防控技术研发提供了科学依据；解决了中国小麦花叶病毒（CWMV）克隆侵染性难题并开启CWMV反向遗传学研究平台；在系统鉴定一个水稻病毒新种的基础上，发现一种细胞间新通道（FL通道）及其介导大尺寸植物病毒运动的功能，拓展了植物细胞学和植物病毒运动的知识。发表学术论文近百篇，其中SCI收录论文50余篇；作为主要完成人，有关的部分结果已获得国家科技进步二等奖1项，浙江省科技进步一等奖1项、二等奖2项，植保科技二等奖1项；参与编写和翻译专著5部；获得国家发明专利授权4项。先后入选浙江省“151人才”第一层次培养人员、浙江省“万人计划”科技创新领军人才和浙江省农科院杰出人才。现兼任国际学术期刊《Scientific Reports》(IF5>4)编委(Editorial Board Member)、《New Phytologist》(IF5>8)顾问委员会委员(Board of Advisors)以及《Plos Pathogen》（IF5>6）、《New Phytologist》(IF5>8)等TOP期刊审稿专家。

联系方式

通讯地址：杭州市德胜中路298号

E-mail：zhanghengmu@zaas.ac.cn 或 zhhengmu@tsinghua.org.cn

近年发表的部分论文（均为通讯作者）

He L, Chen X, Yang J, Zhang TY, Li J, Zhang SB, Zhong KL, Zhang HM, Chen JP, Yang J. Rice black-streaked dwarf virus-encoded P5-1 regulates the ubiquitination activity of SCF E3 ligases and inhibits jasmonate signaling to benefit its infection in rice. New Phytologist. 2020, 225(2): 896-912.

Lv MF, Xie L, Wang HF, Wang HD, Chen JP, Zhang HM. Biology of Southern rice black-streaked dwarf virus: A novel fijivirus emerging in East Asia. Plant Pathology. 2017, 66(4): 515-521.

Xie L, Lv MF, Song XJ, Yang J, Li J, Sun ZT, Zhang YY, Chen JP, Zhang HM. Structure and components of the globular and filamentous viroplasms induced by Rice black-streaked dwarf virus. Micron. 2017, 98: 12-23.

Lv MF, Xie L, Song XJ, Hong J, Mao QZ, Wei TY, Chen JP, Zhang HM. Phloem-limited reoviruses universally induce sieve element hyperplasia and more flexible gateways, providing more channels for their movement in plants. Scientific Reports. 2017, 7: 16467.

Li J, Cai NJ, Xue J, Yang J, Chen JP, Zhang HM. Interaction between southern rice black-streaked dwarf virus minor core protein P8 and a rice zinc finger transcription factor. Archives of Virology. 2017, 162(5): 1261-1273.

Xie L, Lv MF, Yang J, Chen JP, Zhang HM. Genomic and phylogenetic evidence that Maize rough dwarf and Rice black-streaked dwarf fijiviruses should be classified as different geographic strains of a single species. Acta virologica. 2017, 61: 453-462.

Liu XY, Yang J, Xie L, Li J, Song XJ, Chen JP, Zhang HM. The P5-2 of rice black streaked dwarf virus is a non-structural protein targeted to chloroplasts. Archives of Virology. 2015, 160: 1211-1217.

Li J, Xue J, Zhang HM, Yang J, Xie L, Chen JP. Characterization of homologous and heterologous interactions between viroplasm proteins P6 and P9-1 of the fijivirus southern rice black-streaked dwarf virus (SRBSDV). Archives of Virology. 2015, 160: 453-457.

Xie L, Lv MF, Zhang HM, Yang J, Li JM, Chen JP. Tumours induced by a plant virus are derived from vascular tissue and have multiple intercellular gateways that facilitate virus movement. Journal of Experimental Botany. 2014, 65(17): 4873-4886.

Xue J, Li J, Zhang HM, Yang J, Lv MF, Gao BD, Chen JP. Molecular Characterization of Southern Rice Blacked-Streaked Dwarf Virus (SRBSDV) from Vietnam. Journal of Phytopathology. 2014, 162: 349-358.

Wu WQ, Guo XG, Zhang HM, Yang J, Lv MF, Chen JP. Simultaneous Detection and Survey of Three Rice Viruses in China. Plant Disease. 2013, 97(9): 1181-1186.

Li J, Xue J, Zhang HM, Yang J, Lv MF, Xie L, Meng Y, Li PP, Chen JP. Interactions between the P6 and P5-1 proteins of southern rice black-streaked dwarf fijivirus in yeast and plant cells. Archives of Virology, 2013, 158(8): 1649-1659.

Wang Q, Yang J, Zhou GH, Zhang HM, Chen JP, Adams MJ. The Complete Genome Sequence of Two Isolates of Southern Rice black-streaked dwarf virus, a New Member of the Genus Fijivirus. Journal of Phytopathology. 2010, 158: 733-737.

Zhang HM, Yang J, Chen JP, Adams MJ. A black-streaked dwarf disease on rice in China is caused by a novel fijivirus. Archives of Virology. 2008, 153: 1893-1899.

Yang J, Zhang F, Li J, Chen JP, Zhang HM. Integrative analysis of the microRNAome and transcriptome illuminates the response of susceptible rice plants to rice stripe virus. PLOS ONE, 2016, 11(1): e0146946.

Li J, Xiang CY, Yang J, Chen JP, Zhang HM. Interaction of HSP20 with a viral RdRp changes its sub-cellular localization and distribution pattern in plants. Scientific Reports. 2015, 5: 14016.

Yang J, Zhang F, Xie L, Song XJ, Li J, Chen JP, Zhang HM. Functional identification of two minor capsid proteins from Chinese wheat mosaic virus using its infectious full-length cDNA clones. Journal of General Virology. 2016, 97(9): 2441-2450.

Guo LM, He J, Li J, Chen JP, Zhang HM. Chinese wheat mosaic virus: A long-term threat to wheat in China. Journal of Integrative Agriculture. 2019, 18(4): 821-829.

Xie L, Song XJ, Liao ZF, Wu Bin, Yang J, Zhang HM, Hong J. Endoplasmic reticulum remodeling induced by Wheat yellow mosaic virus infection studied by transmission electron microscopy. Micron. 2019, 120: 80-90.

Guo LM, Li J, He J, Liu H, Zhang HM. A class I cytosolic HSP20 of rice enhances heat and salt tolerance in different organisms. Scientific Reports. 2020, 10: 1383.

Lv MF, Xie L, Li YQ, Zhang XM, Li M, Liao ZF, Zhang ZK, Hong J, Zhang HM. Improved quantification of immune-gold labeling and its use to compare the distribution of cellular factors among sub-chloroplast compartments. Micron. 2021, https://doi.org/10.1016/j.micron.2021.103060 (Online).