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 Home ZAAS Institutes The Institute of Virology and Biotechnology Pan Jianzhi
Pan Jianzhi 


2000: Science of Biological production, Gifu University of Japan (Ph. D.)
1992: Science of Environmental Biology, Zhejiang Agricultural University ( M.S.)

1989: Husbandry and Veterinary Science, Zhejiang Agricultural University (B.A.)

Scientific Career and Employment: 

2009-present: Professor, Zhejiang Academy of Agricultural Sciences, China

2007-2009: Senior Research Scientist, RIKEN Bioresource Center, Japan

2005-2007: Research Scientist, RIKEN Bioresource Center, Japan

2002-2005: Collaborative Researcher, RIKEN Bioresource Center, Japan

2000-2002: Postdoctoral Researcher, Dept. of Agricultural Science,Shizuoka University.

Major Publications: 

1. Pan, J, Nakade, K, Huang, Y-C, Zhu Z-W, Masuzaki, S, Hasegawa, H, Murata, T, Yoshiki, A, Yamaguchi, N, Lee, C-H, Yang, W-C, Tsai, E-M, Obata, Y, and Yokoyama, K; Suppression of cell cycle progression by Jun dimerization protein 2 (JDP2) involves down-regulation of cyclin A2. Oncogene 29:6245-6256, 2010.

2. Nakade K, Pan J, Yamasaki T, Noguchi M, Masuzaki S, Kishikawa S, Murata T, Zhu Z, Chen X, Yamaguchi N, Tsai E, Lee J and Yokoyama KK: Role of histone chaperone JDP2 in replicative senescence. Current Topic in Biochemical Research 11(1):75-97, 2009.

3.  Nakade K, Pan J, Yamasaki T, Murata T, Obata Y, Wasylyk B and Yokoyama KK: JDP2 (Jun Dimerization Protein 2)-deficient Mouse Embryonic Fibroblasts Are Resistant to Replicative Senescence. J Biol Chem. 284(16): 10808-17, 2009.

4. Yamasaki T, Akinori Takahashi, Pan J, Yamaguchi N and Yokoyama KK: Phosphorylation of activation transcription factor-2 (ATF-2) at Serine 121 by protein kinase C controls c-Jun-mediated activation of transcription. J Biol Chem. 284(13): 8567-81, 2009.

5. Weidenfeld-Baranboim K, Hasin T, Darlyuk I, Heinrich R, Elhanani O, Pan J, Yokoyama KK, Aronheim A: The ubiquitously expressed bZIP inhibitor, JDP2, suppresses the transcription of it's homologue immediate early gene counterpart, ATF3. Nucleic Acids Res. 37(7): 2194-203, 2009.

6. Nakade K*, Pan *, (*Contributed equally) Yoshiki A, Hideyo Ugai, Kimura M, Shinichi Hatama, Obata Y, Mizuho Iwama, Itohara S, Murata T & Yokoyama KK: JDP2 suppresses adipocyte differentiation by regulating histone acetylation.  Cell death and differentiation 14:1398-405, 2007.

7. Yamasaki T, Murata T, Jin C, Kato K, Noguchi M, Nakade K, Pan J, Nagata K and Yokoyama KK: Assays of nucleosome assembly and the inhibition of histone acetyltransferase activity, Nature Protocol, DOI: 10.1038/nprot. 333-339, 2007.

8. Pan J, Murata T, Yokoyama KK: Introduction of Recombinant Virus Bank (RVB) and application of viral vector for therapeutic study. Cell Technology, 25(5):520-525, 2006.

9. Jin C , Kato K, Chimura T, Yamasaki T , Nakade K, Murata T, Li H, Pan J, Zhao M, Sun K, Chiu R, Ito T, Nagata K, Horikoshi M and Yokoyama KK: Regulation of histone acetylation and nucleosome assembly by transcription factor JDP2. Nature Struct. Mol. Biol., 13(4):331-8, 2006.

10. Ugai, H., Yamasaki, T., Hirose, M., Inabe, K., Kujime, Y., Terashima, M., Liu, B., Tang, H., Zhao, M., Murata, T., Kimura, M., Pan J., Obata, Y., Hamada, H., and Yokoyama, K.: Purification of infectious adenovirus in two hours by ultracentrifugation and tangential flow filtration. Biochem. Biophys. Res. Commun. 331:1053-60, 2005.

11. Pan J, Jin C, Murata T and Yokoyama KK: Histone Modification Activities of JDP2 associated with retinoic Acid-induced differentiation of F9 cells. Nucleic Acids Symp. Ser., 48:189–90, 2004.

12. Suzuki E, Murata T, Watanabe S, Kujime Y, Hirose M, Pan J, Yamazaki T, Ugai H, and Yokoyama KK: A simple method for the simultaneous detection of E1A and E1B in adenovirus stocks. Oncol. Rep. 11:173–8, 2004.

13. Pan J, Sasanami T and Mori M: Stimulation of ZPC Production by Follicle-Stimulating Hormone in the Granulosa Cells of Japanese Quail (Coturnix Japonica). J Poultry Sci., 40:202-11, 2003.

14. Sasanami T, Pan J and Mori M: Expression of perivitelline membrane glycoprotein ZP1 in the liver of Japanese quail (Coturnix japonica) after in vivo treatment with diethylstilbestrol. J. Steroid. Biochem. Mol. Biol., 84(1): 109-16, 2003.

15. Pan J, Jin C, Murata T, and Yokoyama KK: Sequence specific transcription factor, JDP2 interacts with histone and inhibits p300-mediated histone acetylation. Nucleic Acids. Res. Suppl., 3: 305-306, 2003.

16. Saito S, Sawai K, Ugai H, Moriyasu S, Minamihashi A, Yamamoto Y, Hirayama H, Kageyama S, Pan J, Murata T, Kobayashi Y, Obata Y, Yokoyama KK: Generation of cloned calves and transgenic chimeric embryos from bovine embryonic stem-like cells. BBRC, 309(1):104-13, 2003.

17. Sasanami T, Pan J, Doi Y, Hisada M, Kohsaka T, Toriyama M and Mori M: Secretion of egg envelope protein ZPC after carboxy-terminal proteolytic processing in quail granulosa cells. Eur. J. Biochem., 269(8): 2223-31, 2002.

18. Pan J, Sasanami T, Kono Y, Matsuda T, Mori M: Effects of testosterone on production of perivitelline membrane glycoprotein ZPC by granulosa cells of Japanese quail (Coturnix japonica). Biol. Reprod., 64(1): 310-6, 2001.

19. Pan J, Sasanami T, Nakajima S, Kido S, Doi Y, Mori M: Characterization of progressive changes in ZPC of the vitelline membrane of quail oocyte following oviductal transport. Mol. Reprod. Dev., 55 (2):175-181, 2000.

20. Pan J, Sasanami T and Mori M: Effect of testosterone on perivitelline membrane protein (ZPC) production in the cultured quail granulosa cells. Recent Advances in Comparative Endocrinology, 196-206, 2000.

1. Pan, J, Nakade, K, Huang, Y-C, Zhu Z-W, Masuzaki, S, Hasegawa, H, Murata, T, Yoshiki, A, Yamaguchi, N, Lee, C-H, Yang, W-C, Tsai, E-M, Obata, Y, and Yokoyama, K; Suppression of cell cycle progression by Jun dimerization protein 2 (JDP2) involves down-regulation of cyclin A2. Oncogene 29:6245-6256, 2010.

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